Dynamic Changes in DNA Methylation in Ischemic Tolerance
نویسندگان
چکیده
منابع مشابه
Dynamic Changes in DNA Methylation in Ischemic Tolerance
Epigenetic mediators of gene expression are hypothesized to regulate transcriptomic responses to preconditioning ischemia and ischemic tolerance. Here, we utilized a methyl-DNA enrichment protocol and sequencing (ChIP-seq) to identify patterns of DNA methylation in an established model of ischemic tolerance in neuronal cultures (oxygen and glucose deprivation: OGD). We observed an overall decre...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2015
ISSN: 1664-2295
DOI: 10.3389/fneur.2015.00102